Diagnosis and Clinical Presentation
Acute febrile neutrophilic dermatosis should be considered in children and adults with acute onset of persistent high fever, arthralgias, general malaise, and generally ill appearance, elevated white blood cell count, negative blood cultures, and the presence of a skin eruption comprised of red painful edematous papules, plaques, bullae, and pustules that typically start on the distal extremities and then disseminate.
- Herron MD, Coffin CM, Vanderhooft SL: Sweet Syndrome in Two Children. Pediatr Dermatol Volume 22, Issue 6, 2005; 525-529.
- Waltz KM, Long D, Marks JG Jr, Billingsley EM: Sweet's syndrome and erythema nodosum: the simultaneous occurrence of two reactive dermatoses. Arch Dermatol 1999; 135: 62 - 66.
- Herron MD, Coffin CM, Vanderhooft SL: Sweet Syndrome in Two Children. Pediatric Dermatology Volume 22, Issue 6, 2005; 525-529.
- Nischal KC, Khopkar U: An approach to the diagnosis of neutrophilic dermatoses: A histopathological perspective. Indian J Dermatol Venereol Leprol 2007; 73:222-30.
- Cohen PR: Sweet’s syndrome - a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J of Rare Diseases 2007; 2:34